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Erectile Dysfunction and Cialis Today, drugs like Cialis have made it possible to treat previously untreatable erectile dysfunctions and are helping millions of people lead a normal and healthy sex life. Erectile dysfunction is the basis of a multi-billion dollar industry. To understand an erectile dysfunction better, it is important to understand how a normal erection occurs. Contrary to popular belief, the brain is the biggest sex organ and all conscious erections are the result of an impulse sent by the brain to the nervous system (the cause of night or sleep erections is still not completely understood). The nervous system then tells the muscular part of the penis the corpus cavernosum to relax.